NFL Matchups: Predictions, Odds & Betting Trends

Sun, 9/14, Final: 26 – 21
San Francisco 49ers @ New Orleans Saints

49ers: 1-0 (100.0%) - NFC West

Saints: 0-1 (0.0%) - NFC South

Line: +3.0

Total: 40.5

Open: +7

Open: 44.5

Team totals: 49ers 21.5 · Saints 19.5

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Notes

49ers

Situational Factor(s)

Lookahead: next game versus division rival

Baller System(s)

Back favorite off a game as a fav w/ low turnovers

Saints

Nothing active

Baller Index Our Exclusive NFL Baller Index is a blend of several regressions, weighted to different cross-sections of the season. These regressions essentially look for teams that have over- or under-performed, in terms of points scored, relative to what would be expected based on their underlying metrics and who might be in for regression. While it does not factor in injuries, situational spots, or historic matchups into account, it can be a good place to start when thinking about a particular matchup.

The model doesn't have enough games played yet this season to generate reliable predictions — it typically won't start producing projections until Week 3.

Filters

Team Comparison Stats, Records and the sections tied to them follow these filters; each team's Schedule and Historical Matchups follow them when their switch is on.

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Schedules

49ers Schedule Follow global filters

Date	Team	Points		Opponent	Opp Pts	Yds	Rush	Rec	Int	Fum	Line	Total	Margin	Act Total
09/28/25 2025	49ers	-	vs.	Jaguars	-	-	-	-	-	-	-3.5	45.5	-	-
09/21/25 2025	49ers	-	vs.	Cardinals	-	-	-	-	-	-	-1.5	44.5	-	-
09/14/25 2025	49ers	-	@	Saints	-	-	-	-	-	-	-3.0	40.5	-	-
09/07/25 2025	49ers	17	@	Seahawks	13	396	119	277	0	1	-2.5	43.5	-4	U 30 -13.5
Last season · shown for reference, not in the averages
01/05/25 2024	49ers	24	@	Cardinals	47	464	138	326	0	3	+5.5	43.5	+23	O 71 +27.5
12/30/24 2024	49ers	34	vs.	Lions	40	487	75	412	0	2	+4.0	50.5	+6	O 74 +23.5
12/22/24 2024	49ers	17	@	Dolphins	29	394	81	313	0	0	-2.0	44.0	+12	O 46 +2.0
12/12/24 2024	49ers	6	vs.	Rams	12	205	63	142	0	0	-3.0	48.5	+6	U 18 -30.5
12/08/24 2024	49ers	38	vs.	Bears	13	456	131	325	0	0	-3.0	43.5	-25	O 51 +7.5
12/01/24 2024	49ers	10	@	Bills	35	247	153	94	0	3	+6.5	45.5	+25	U 45 -0.5
11/24/24 2024	49ers	10	@	Packers	38	243	44	199	0	5	+6.5	44.5	+28	O 48 +3.5
11/17/24 2024	49ers	17	vs.	Seahawks	20	290	131	159	1	0	-6.0	48.5	+3	U 37 -11.5
11/10/24 2024	49ers	23	@	Buccaneers	20	428	75	353	0	2	-6.5	50.5	-3	U 43 -7.5

Away Games Avg (1 game this season)		17.0	-	-	13.0	396	119	277	0.0	1.0	-2.5	43.5	-4.0 +1.5	U 30.0 -13.5

All Games Avg (1 game this season)		17.0	-	-	13.0	396	119	277	0.0	1.0	-2.5	43.5	-4.0 +1.5	U 30.0 -13.5

Saints Schedule Follow global filters

Date	Team	Points		Opponent	Opp Pts	Yds	Rush	Rec	Int	Fum	Line	Total	Margin	Act Total
09/28/25 2025	Saints	-	@	Bills	-	-	-	-	-	-	+14.5	48.5	-	-
09/21/25 2025	Saints	-	@	Seahawks	-	-	-	-	-	-	+7.5	41.5	-	-
09/14/25 2025	Saints	-	vs.	49ers	-	-	-	-	-	-	+3.0	40.5	-	-
09/07/25 2025	Saints	13	vs.	Cardinals	20	321	107	214	0	0	+5.5	44.5	+7	U 33 -11.5
Last season · shown for reference, not in the averages
01/05/25 2024	Saints	19	@	Buccaneers	27	304	64	240	1	0	+14.5	44.5	+8	O 46 +1.5
12/29/24 2024	Saints	10	vs.	Raiders	25	299	81	218	0	2	+2.0	37.5	+15	U 35 -2.5
12/23/24 2024	Saints	0	@	Packers	34	220	67	153	0	2	+14.5	44.0	+34	U 34 -10.0
12/15/24 2024	Saints	19	vs.	Commanders	20	274	69	205	0	0	+7.5	44.5	+1	U 39 -5.5
12/08/24 2024	Saints	14	@	Giants	11	311	92	219	1	2	-4.5	40.5	-3	U 25 -15.5
12/01/24 2024	Saints	14	vs.	Rams	21	327	143	184	0	0	+2.5	48.5	+7	U 35 -13.5
11/17/24 2024	Saints	35	vs.	Browns	14	480	214	266	0	2	+1.0	44.0	-21	O 49 +5.0
11/10/24 2024	Saints	20	vs.	Falcons	17	365	96	269	1	1	+3.5	46.5	-3	U 37 -9.5
11/03/24 2024	Saints	22	@	Panthers	23	433	197	236	1	0	-7.0	43.0	+1	O 45 +2.0

Home Games Avg (1 game this season)		13.0	-	-	20.0	321	107	214	0.0	0.0	+5.5	44.5	+7.0 -1.5	U 33.0 -11.5

All Games Avg (1 game this season)		13.0	-	-	20.0	321	107	214	0.0	0.0	+5.5	44.5	+7.0 -1.5	U 33.0 -11.5

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Records

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Notable Trends

Notable trends will be listed here starting Week 4.

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Saints (Home)

The Saints are 0% (0-1) against the spread

The Saints are 0% (0-1) against the spread at home

The Saints are 0% (0-1) against the spread as a dog

The Saints are 0% (0-1) against the spread as a home dog

The Saints are 100% (1-0) to the under

The Saints are 100% (1-0) to the under at home

The Saints are 100% (1-0) to the under as a dog

The Saints are 100% (1-0) to the under as a home dog

The Saints are 0% (0-1) (L30 days) against the spread

The Saints are 0% (0-1) (L30 days) against the spread at home

The Saints are 0% (0-1) (L30 days) against the spread as a dog

The Saints are 0% (0-1) (L30 days) against the spread as a home dog

The Saints are 100% (1-0) (L30 days) to the under

The Saints are 100% (1-0) (L30 days) to the under at home

The Saints are 100% (1-0) (L30 days) to the under as a dog

The Saints are 100% (1-0) (L30 days) to the under as a home dog

49ers (Away)

The 49ers are 100% (1-0) against the spread

The 49ers are 100% (1-0) against the spread away

The 49ers are 100% (1-0) against the spread as a fav

The 49ers are 100% (1-0) against the spread as an away fav

The 49ers are 100% (1-0) to the under

The 49ers are 100% (1-0) to the under away

The 49ers are 100% (1-0) to the under as a fav

The 49ers are 100% (1-0) to the under as an away fav

The 49ers are 100% (1-0) (L30 days) against the spread

The 49ers are 100% (1-0) (L30 days) against the spread away

The 49ers are 100% (1-0) (L30 days) against the spread as a fav

The 49ers are 100% (1-0) (L30 days) against the spread as an away fav

The 49ers are 100% (1-0) (L30 days) to the under

The 49ers are 100% (1-0) (L30 days) to the under away

The 49ers are 100% (1-0) (L30 days) to the under as a fav

The 49ers are 100% (1-0) (L30 days) to the under as an away fav

Historical Matchups (Last 3 Seasons, Max 10) Follow global filters

Date	Team	Pts		Opponent	Pts	Yds	Rush	Rec	Int	Fum	Line	Total	Margin	Act Total
11/27/22 2022	Saints	0	@	49ers	13	318	96	222	0	0	+9.0	43.5	+13	U 13 -30.5

All Games Avg (1 games)		0.0	-	-	13.0	318	96	222	0.0	0.0	+9.0	43.5	+13.0 -4.0	U 13.0 -30.5