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Updated: 11/11/26 1:23 p.m. ET
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NFL Matchups: Predictions, Odds & Betting Trends

Sun, 12/1, Final: 25 – 24
Indianapolis Colts @ New England Patriots
Colts: 5-7 (41.7%) - AFC South
Patriots: 3-9 (25.0%) - AFC East
Line: +2.5
Total: 41.0
Open: +2.5
Open: 43
Team totals: Colts 21.5 · Patriots 20.5