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NFL Matchups: Predictions, Odds & Betting Trends

Sun, 9/29, Final: 13 – 30
New England Patriots @ San Francisco 49ers

Patriots: 1-2 (33.3%) - AFC East

49ers: 1-2 (33.3%) - NFC West

Line: -10.5

Total: 42.5

Open: -9.5

Open: 40.5

Team totals: Patriots 14.5 · 49ers 26.5