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Updated: 11/11/26 2:13 p.m. ET
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NFL Matchups: Predictions, Odds & Betting Trends

Sun, 12/17, Final: 45 – 29
San Francisco 49ers @ Arizona Cardinals
49ers: 10-3 (76.9%) - NFC West
Cardinals: 3-10 (23.1%) - NFC West
Line: +12.5
Total: 48.5
Open: +13.5
Open: 46
Team totals: 49ers 30.5 · Cardinals 17.5
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Notes — no active systems for this matchup.

Baller Index Our Exclusive NFL Baller Index is a blend of several regressions, weighted to different cross-sections of the season. These regressions essentially look for teams that have over- or under-performed, in terms of points scored, relative to what would be expected based on their underlying metrics and who might be in for regression. While it does not factor in injuries, situational spots, or historic matchups into account, it can be a good place to start when thinking about a particular matchup.
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Filters
Team Comparison Stats, Records and the sections tied to them follow these filters; each team's Schedule and Historical Matchups follow them when their switch is on.
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Schedules
49ers Schedule
Date Team Points Opponent Opp Pts Yds Rush Rec Int Fum Line Total Margin Act Total
12/31/23
2023
49ers - @ Commanders - - - - - - -14.0 48.5 - -
12/25/23
2023
49ers - vs. Ravens - - - - - - -6.5 47.0 - -
12/17/23
2023
49ers - @ Cardinals - - - - - - -12.5 48.5 - -
12/10/23
2023
49ers 28 vs. Seahawks 16 541 173 368 2 1 -14.5 44.5 -12 U 44 -0.5
12/03/23
2023
49ers 42 @ Eagles 19 460 146 314 0 1 -3.0 46.5 -23 O 61 +14.5
11/23/23
2023
49ers 31 @ Seahawks 13 378 169 209 1 1 -7.0 43.0 -18 O 44 +1.0
11/19/23
2023
49ers 27 vs. Buccaneers 14 448 115 333 1 0 -13.5 42.0 -13 U 41 -1.0
11/12/23
2023
49ers 34 @ Jaguars 3 446 144 302 2 0 -3.0 42.5 -31 U 37 -5.5
10/29/23
2023
49ers 17 vs. Bengals 31 478 113 365 0 1 -4.5 44.5 +14 O 48 +3.5
10/23/23
2023
49ers 17 @ Vikings 22 337 65 272 1 1 -7.0 43.0 +5 U 39 -4.0
10/15/23
2023
49ers 17 @ Browns 19 233 108 125 2 1 -9.5 36.0 +2 P 36 0.0
10/08/23
2023
49ers 42 vs. Cowboys 10 423 170 253 3 1 -3.5 45.0 -32 O 52 +7.0
10/01/23
2023
49ers 35 vs. Cardinals 16 407 124 283 0 0 -14.5 44.0 -19 O 51 +7.0
Away Games Avg
(5 games)
28.2 - - 15.2 371 126 244 1.2 0.8 -5.9 42.2 -13.0 +7.1 O 43.4 +1.2
All Games Avg
(10 games)
29.0 - - 16.3 415 133 282 1.2 0.7 -8.0 43.1 -12.7 +4.7 O 45.3 +2.2
Cardinals Schedule
Date Team Points Opponent Opp Pts Yds Rush Rec Int Fum Line Total Margin Act Total
12/31/23
2023
Cardinals - @ Eagles - - - - - - +11.5 47.0 - -
12/24/23
2023
Cardinals - @ Bears - - - - - - +4.5 42.0 - -
12/17/23
2023
Cardinals - vs. 49ers - - - - - - +12.5 48.5 - -
12/03/23
2023
Cardinals 24 @ Steelers 10 295 150 145 0 2 +6.0 41.0 -14 U 34 -7.0
11/26/23
2023
Cardinals 14 vs. Rams 37 329 73 256 1 0 +3.0 44.5 +23 O 51 +6.5
11/19/23
2023
Cardinals 16 @ Texans 21 337 123 214 3 2 +5.5 48.0 +5 U 37 -11.0
11/12/23
2023
Cardinals 25 vs. Falcons 23 371 122 249 0 0 +2.0 43.5 -2 O 48 +4.5
11/05/23
2023
Cardinals 0 @ Browns 27 99 41 58 0 1 +12.5 38.0 +27 U 27 -11.0
10/29/23
2023
Cardinals 24 vs. Ravens 31 337 129 208 0 1 +9.5 45.0 +7 O 55 +10.0
10/22/23
2023
Cardinals 10 @ Seahawks 20 277 127 150 1 2 +9.0 44.0 +10 U 30 -14.0
10/15/23
2023
Cardinals 9 @ Rams 26 365 130 235 0 1 +7.0 48.0 +17 U 35 -13.0
10/08/23
2023
Cardinals 20 vs. Bengals 34 308 142 166 1 1 +3.0 45.5 +14 O 54 +8.5
10/01/23
2023
Cardinals 16 @ 49ers 35 370 105 265 0 1 +14.5 44.0 +19 O 51 +7.0
Home Games Avg
(4 games)
20.8 - - 31.3 336 117 220 0.5 0.5 +4.4 44.6 +10.5 -6.1 O 52.0 +7.4
All Games Avg
(10 games)
15.8 - - 26.4 309 114 195 0.6 1.1 +7.2 44.2 +10.6 -3.4 U 42.2 -2.0
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Records
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Notable Trends
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Historical Matchups (Last 3 Seasons, Max 10)
Date Team Pts Opponent Pts Yds Rush Rec Int Fum Line Total Margin Act Total
10/01/23
2023
Cardinals 16 @ 49ers 35 407 124 283 0 0 +14.5 44.0 +19 O 51 +7.0
01/08/23
2022
Cardinals 13 @ 49ers 38 347 169 178 3 0 +14.5 40.0 +25 O 51 +11.0
11/21/22
2022
Cardinals 10 vs. 49ers 38 344 67 277 0 1 +9.5 43.0 +28 O 48 +5.0
11/07/21
2021
Cardinals 31 @ 49ers 17 365 39 326 0 2 +3.0 45.0 -14 O 48 +3.0
10/10/21
2021
Cardinals 17 vs. 49ers 10 333 94 239 1 4 -5.0 48.5 -7 U 27 -21.5
12/26/20
2020
Cardinals 12 vs. 49ers 20 367 120 247 0 2 -6.0 49.0 +8 U 32 -17.0
09/13/20
2020
Cardinals 24 @ 49ers 20 382 123 259 1 0 +6.5 48.5 -4 U 44 -4.5
Cardinals as Home
(3 games)
13.0 - - 22.7 348 94 254 0.3 2.3 -0.5 46.8 +9.7 -10.2 U 35.7 -11.2
All Games Avg
(7 games)
17.6 - - 25.4 364 105 258 0.7 1.3 +5.3 45.4 +7.9 -2.6 U 43.0 -2.4