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Updated: 11/10/26 2:08 p.m. ET
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NFL Matchups: Predictions, Odds & Betting Trends

Sun, 11/26, Final: 20 – 27
Tampa Bay Buccaneers @ Indianapolis Colts
Buccaneers: 4-6 (40.0%) - NFC South
Colts: 5-5 (50.0%) - AFC South
Line: -2.5
Total: 45.0
Open: -1.5
Open: 42
Team totals: Buccaneers 21.5 · Colts 23.5