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Updated: 11/10/26 2:28 p.m. ET
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NFL Matchups: Predictions, Odds & Betting Trends

Sun, 10/29, Final: 38 – 27
New Orleans Saints @ Indianapolis Colts
Saints: 3-4 (42.9%) - NFC South
Colts: 3-4 (42.9%) - AFC South
Line: +2.0
Total: 43.5
Open: +1.5
Open: 40
Team totals: Saints 22.5 · Colts 20.5