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NFL Matchups: Predictions, Odds & Betting Trends

Sun, 10/22, Final: 25 – 29
Buffalo Bills @ New England Patriots

Bills: 4-2 (66.7%) - AFC East

Patriots: 1-5 (16.7%) - AFC East

Line: +7.5

Total: 41.5

Open: +8.5

Open: 43.5

Team totals: Bills 24.5 · Patriots 16.5