| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| SF | 14 | 10 | 10 | 14 | 48 |
| IND | 7 | 10 | 3 | 7 | 27 |
| SF | IND | |
|---|---|---|
| First downs | 28 | 19 |
| Total yards | 440 | 335 |
| Passing yards | 295 | 277 |
| Rushing yards | 145 | 58 |
| Rushes | 31 | 20 |
| 3rd down | 7-11 | 5-10 |
| 4th down | 1-1 | 0-1 |
| Interceptions thrown | 1 | 1 |
| Fumbles | 1 | 2 |
| Penalties-yards | 2-36 | 6-45 |
| Time of possession | 33:05 | 26:55 |
| Passing | Pos | C/ATT | YDS | AVG | TD | INT |
|---|---|---|---|---|---|---|
| Brock Purdy | QB | 25/34 | 295 | 8.7 | 5 | 1 |
| Rushing | Pos | CAR | YDS | AVG | TD |
|---|---|---|---|---|---|
| Christian McCaffrey | RB | 21 | 117 | 5.6 | 0 |
| Brian Robinson | RB | 5 | 20 | 4.0 | 0 |
| Brock Purdy | QB | 2 | 11 | 5.5 | 0 |
| Mac Jones | QB | 3 | -3 | -1.0 | 0 |
| Receiving | Pos | REC | TGT | YDS | AVG | TD |
|---|---|---|---|---|---|---|
| George Kittle | TE | 7 | 8 | 115 | 16.4 | 1 |
| Jauan Jennings | WR | 5 | 6 | 71 | 14.2 | 1 |
| Christian McCaffrey | RB | 6 | 8 | 29 | 4.8 | 2 |
| Kendrick Bourne | WR | 3 | 5 | 27 | 9.0 | 0 |
| Demarcus Robinson | WR | 2 | 2 | 23 | 11.5 | 1 |
| Skyy Moore | WR | 1 | 1 | 23 | 23.0 | 0 |
| Jake Tonges | TE | 1 | 2 | 7 | 7.0 | 0 |
| Brian Robinson | RB | 0 | 1 | 0 | 0 |
| Kicking | Pos | FG | XP | PTS |
|---|---|---|---|---|
| Eddy Pineiro | K | 2/3 | 6/6 | 12 |
| Passing | Pos | C/ATT | YDS | AVG | TD | INT |
|---|---|---|---|---|---|---|
| Philip Rivers | QB | 23/35 | 277 | 7.9 | 2 | 1 |
| Riley Leonard | QB | 0/1 | 0 | 0.0 | 0 | 0 |
| Rushing | Pos | CAR | YDS | AVG | TD |
|---|---|---|---|---|---|
| Jonathan Taylor | RB | 16 | 46 | 2.9 | 1 |
| Tyler Goodson | RB | 3 | 9 | 3.0 | 0 |
| Josh Downs | WR | 1 | 3 | 3.0 | 0 |
| Receiving | Pos | REC | TGT | YDS | AVG | TD |
|---|---|---|---|---|---|---|
| Alec Pierce | WR | 4 | 4 | 86 | 21.5 | 2 |
| Josh Downs | WR | 5 | 9 | 65 | 13.0 | 0 |
| Jonathan Taylor | RB | 3 | 3 | 33 | 11.0 | 0 |
| Michael Pittman | WR | 4 | 5 | 32 | 8.0 | 0 |
| Tyler Warren | TE | 3 | 9 | 30 | 10.0 | 0 |
| Mo Alie-Cox | TE | 2 | 2 | 16 | 8.0 | 0 |
| Andrew Ogletree | TE | 1 | 2 | 11 | 11.0 | 0 |
| Ameer Abdullah | RB | 1 | 1 | 4 | 4.0 | 0 |
| Coleman Owen | WR | 0 | 1 | 0 | 0 |
| Kicking | Pos | FG | XP | PTS |
|---|---|---|---|---|
| Blake Grupe | K | 2/2 | 3/3 | 9 |
Player lines cover passing, rushing, receiving and kicking; defensive players' stats are not stored. Fumbles are the team's.
